Open access article: (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408756/ )

Abstract

Autism spectrum disorders (ASD) constitute a public health concern with increasing prevalence worldwide. We aimed to estimate prevalence and age at diagnosis in Greece, where no large-scale prevalence study has ever been conducted. Aggregate data were collected on ASD diagnoses by gender and calendar year of diagnosis up to 2019, for children born in 2008 and 2009, from the Centers for Educational and Counseling Support, which evaluate children to receive special educational support in school. Coverage was 87.1% of centers and 88.1% of schoolchildren born in 2008–9. ASD prevalence overall was 1.15% (1.83% males, 0.44% females; ratio 4.14:1), ranging from 0.59% to 1.50% in Greece’s 13 regions. In five regions, prevalence differed significantly between centers. Overall, only 3.8% of diagnoses were made before the fourth year after birth and 42.7% before the sixth year, with considerable variation between regions. Approximate mean age at diagnosis was six years and one month, and about three months earlier for girls than for boys. Our results provide evidence-based information to guide service planning and development at national and regional levels. Particular attention should be paid to smoothing out inequalities regarding service accessibility and provision. Emphasis should be given to earlier identification and diagnosis of ASD.

Citation: Thomaidis L, Mavroeidi N, Richardson C, Choleva A, Damianos G, Bolias K, Tsolia M. Autism Spectrum Disorders in Greece: Nationwide Prevalence in 10-11 Year-Old Children and Regional Disparities. J Clin Med. 2020 Jul 8;9(7):2163. doi: 10.3390/jcm9072163. PMID: 32650567; PMCID: PMC7408756.

Open access article: (https://www.mednet.gr/archives/2022-3/pdf/308.pdf)

Abstract

Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental disorder which has attracted the interest of researchers in many scientific fields. The prevalence of a disease or a disorder is important for healthcare and socio-economic reasons. According to the World Health Organization (WHO), currently, 1 in 160 children is born with ASD (0.63%), possibly a conservative estimate, as many studies have reported a prevalence higher than 1%. Even so, the WHO rate is approximately 14 times higher than that reported in the first epidemiological study on ASD, which was conducted in the UK 50 years ago. It is currently estimated that approximately 60 million people worldwide have ASD. Diagnosis and documentation of these individuals is challenging, due to the nature of the disorder and its broad spectrum. Many countries have no epidemiological data on ASD and several epidemiological studies on ASD record significant methodological limitations, but the currently available data indicate that the prevalence of ASD has risen over the years. The interpretation of this trend remains uncertain, but several factors have been documented that may have contributed to this apparent increase, including revision of the diagnostic criteria, overdiagnosis, scientific advances, accessibility to services, increase in social awareness, and improvement in the methodology applied in the epidemiological studies, in addition to environmental and other factors.

Citation: Depastas, C., Kalaitzaki, A. (2022). The epidemiology of autism spectrum disorder and factors contributing to the increase in its prevalence. A.Archives of Hellenic Medicine / Arheia Ellenikes Iatrikes . May/Jun2022, Vol. 39 Issue 3, p308-312. 5p.

 Open access article: (https://sanp.ch/article/doi/sanp.2020.03084 )

Abstract

Once considered to be rare with a prevalence of 4–5/10,000, autism today has a prevalence in the range of 0.9–1.5%. The increased prevalence reflects mostly a broadening of the diagnosis, and improved awareness and identification among children. The hypothesis that the rise in autism prevalence was due to increased use of childhood vaccines has been refuted in well-controlled and replicated studies. Few environmental causes are well established (advanced paternal age, prenatal exposure to valproate); most other findings require replication.

Citations: Eric Fombonne, (2020). Epidemiological controversies in autism. Swiss Arch Neurol Psychiatr Psychother. 2020;171:w03084